Proceedings of the National Academy of Sciences. S-Nitrosylation of CRTC1 in Alzheimer's disease impairs CREB-dependent gene ...

To determine whether light elicited CRE-mediated gene expression ... A second P-ERK-specific antibody was used for P-ERK/P-CREB double-labeling experiments. The tissue was incubated with a ...

They also discovered that the function of the CREB gene, implicated in human depression and known to promote either resilience vs susceptibility to stress in two distinct brain regions ...

Given the vast amount of knowledge today about how signal-transcription cascades regulate gene expression ... but the transcription factor CREB, which binds cAMP-response elements in the promoters ...