This research focuses on the cAMP-response element binding protein (CREB), a transcription factor known to regulate genes ...

and TRP-2 at the mRNA and protein levels by regulating both the MAPK and protein kinase A (PKA)/cAMP response element-binding protein (CREB) signaling pathways. Ligustroside also suppressed the ...

Figure 4: Photic stimulation results in nuclear co-localization of P-ERK and P-CREB in the SCN. Figure 5: Glutamate triggers ERK activation in SCN slice and SCN-enriched primary neuron cultures.