To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...

The most straightforward way to examine the pattern of Cre-mediated recombination in the various tissues of the mouse is Southern blot analysis distinguishing wild-type, loxP-flanked and ...

We analyzed 18 cNTS-Cre mouse lines and cataloged the dynamics of nine cNTS cell types during feeding." The researchers ...