The cerebella from c-kit IRES-Cre mice injected with Cre-reporter virus at PND (pups shortly after birth) 0 or PND 64. Tissue was prepared from animals 27 and 14 days after injection ...

To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...

A current search for Cre recombinase transgenic mice in Medline yields over 900 publications, more than half of which were published in 2003 or later. In view of this popularity, it appears ...

They also demonstrated that this technology can be applied to newts and mice. While continuing their research on newt ...

A new vector has been developed that integrates the Cre enzyme gene with its target DNA sequence, loxP, enabling the creation of Cre-loxP organisms in a single step.