The global pattern of methylation in mammals makes it difficult to determine whether methylation is targeted to certain gene sequences or is a default state, but the CpG islands tend to be near ...
Pyro Q-CpG is attractive for the analysis of CpG methylation because it is capable of quantifying methylation in explicit sequence context, and is fast and easy to perform. Assay design is ...
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New study challenges longstanding assumption about the cause of the genome's most common mutationMore information: Marketa Tomkova et al, Human DNA polymerase ε is a source of C>T mutations at CpG dinucleotides, Nature Genetics (2024). DOI: 10.1038/s41588-024-01945-x Provided by Ludwig ...
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