Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing how it transports retinoids and fatty ...

Scientists have for the first time looked deep into the protein structure that may determine our vision—and discovered that it is much more dynamic than previously thought. RBP3 not only changes its ...

RBP3 plays a key role in delivering all-trans-retinol (at-ROL) from photoreceptors to the retinal pigment epithelium, where it is converted into 11-cis-retinal (11c-RAL), a key molecule for vision.

Proteins are fundamental biomolecules that perform a broad range of vital functions within the human body. They serve as an essential structural and functional component of cells, tissues and organs ...

Previous studies suggest that schizophrenia not only reduces the volume of gray matter in the brains of those affected, but that it also leads to loss of retinal tissue. However, whether these ...

After absorbing light, it collapses. The retinal in rhodopsin is in a curved cis-isomeric form. A quantum of light in a fantastically short time, about 50-100 femtoseconds, isomerizes (straightens) it ...

Although millions of people worldwide suffer from retinal degeneration-associated blindness, no curative treatment is available. 1 Stem cell therapies hold promise for promoting regeneration. Retinal ...

Once inside retinal cells, the functional RPE65 protein enables the regeneration of 11-cis-retinal, which improves light detection and restores vision. In healthy individuals, RPE65 in retinal ...

Once inside retinal cells, the functional RPE65 protein enables the regeneration of 11-cis-retinal, which improves light detection and restores vision. In healthy individuals, RPE65 in retinal ...