It's a new state of fatigue that has lasted for at least 6 months. CFS is more than feeling tired all the time. It comes with a lot of other symptoms that can make it hard to handle daily life.

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

Conditions like myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and more recently, long COVID, are the sources of significant confusion and contention among researchers, clinicians ...

The researchers analysed the biological samples and symptoms of more than 1000 people with chronic fatigue syndrome (CFS) and compared them with tens of thousands of people with other conditions.