Blocking CKIα, CDK7, and CDK9 augments and synergistically stabilizes p53 and down regulates Myc and MCL1 promoting the rapid killing of leukemia cells as well as leukemic stem cells. Pre ...

Immune function analysis showed that HDAC2-AS2 in EVs was taken up by CD8 + T cells, where it binds to intracellular cyclin-dependent kinase 9 (CDK9), leading to a reduction in intracellular CDK9 ...