It was recently discovered by the Taatjes lab, working with the Kovarik lab (MPL, Vienna), that the Mediator kinases (CDK8 and its paralog CDK19) are key regulators of the interferon response. While ...

University of Colorado Cancer Center study shows how TIP60 and CDK8 cooperate to regulate HIF1A, allowing tumors to survive low-oxygen environments. Disclaimer: AAAS and EurekAlert! are not ...