The research team points to one particular protein that—like a blanket thrown on a patch of growing flames—seems to smother all those transcription factors at once when CDK7 is inhibited.

Cancer drugs that inhibit CDK7 rapidly shut down pathways responsible for cell proliferation within minutes. For organs to develop, grow, and regenerate, cells must divide and multiply, a process ...

The research team points to one particular protein that, like a blanket thrown on a patch of growing flames, seems to smother all those transcription factors at once when CDK7 is inhibited.

Blocking CKIα, CDK7, and CDK9 augments and synergistically ... targeting chimeric molecules (PHM-PTCs) that degrade protein targets with a high probability of success. Kyle Chan, BioTheryX ...

BTX-A51 is a first-in-class, small molecule kinase inhibitor that co-targets casein kinase 1 alpha (CK1α and cyclin-dependent kinases 7 and 9 (CDK7 and CDK9), three master regulators of cancer ...

The research team points to one particular protein that, like a blanket thrown on a patch of growing flames, seems to smother all those transcription factors at once when CDK7 is inhibited.