Malfunctioning of the enzyme CDK7 is crucial to many cancers, making drugs that target it a high priority. Despite some ...

In this context, a study appearing in Frontiers of Medicine explores the potential of dronedarone, an FDA-approved drug, in inhibiting ESCC proliferation through the CDK4/CDK6-RB1 axis ...

While the global CDK4/6 inhibitor market remains highly competitive, VERZENIO's distinct clinical advantages and ongoing studies could contribute to further market expansion. VERZENIO (abemaciclib ...

"Addition of metformin to letrozole and abemaciclib is feasible and safe, and appears to induce deeper responses, including complete responses not reported with any of the previous CDK4/6 ...