NG-348 encodes two immunomodulatory membrane-integrated T cell proteins: a membrane-anchored, full-length human CD80 and a membrane-anchored antibody fragment specific for the T cell receptor CD3 ...

The infusion of large numbers of antigen-specific cytotoxic T lymphocytes (CTLs ... complexes along with CD80, CD54, and CD58 by retroviral transduction. These cells could be efficiently expanded ...