CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

CERo Therapeutics (CERO) announces the allowance of two patent applications submitted to the U.S. Patent and Trademark Office, USPTO, which ...

In the Phase I trial, "RNA neoantigen vaccines prime long-lived CD8 + T cells in pancreatic cancer ... T cell receptor (TCR) sequencing, and longitudinal blood and tissue analyses over a median ...

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders ...

The binding of the TCR triggers a cascade of molecular events that leads to an immune response. During antigen recognition, CD4 or CD8 molecules act as co-receptors, strengthening the bond between ...

The CD8+ T cell activation involves two key interactions: The TCR/pMHCI interaction: determines antigen specificity. Promiscuity is a characteristic feature of this interaction and it is essential for ...