and CD8-positive suppressor T cells, which restrain certain types of immune response. On 23–26 September 2024, the second ImmunOctoberfest conference took place in Raitenhaslach, Germany ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells ... Their work showed that the small intestine holds two types of T RM cells. These cells are split between ...

In fact, previous studies have reported that granzyme B (GZMB)-expressing CD8+ T-cells have induce type 1 diabetes by killing pancreatic beta cells. Comparatively, GZMB-expressing KIR+ CD8+ T ...

The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease. In a new study published in Nature, led by scientists at the Allen ...

There are two main types of lymphocytes ... immune cells to infectious pathogens such as bacteria and viruses. CD8 T-cells which have molecules on their surface called CD8. These are the "killer ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Type 1 diabetes raises important questions about immune cell activity that have broad implications for immunotherapy. Philip M and Schietinger A. CD8 T cell differentiation and dysfunction in cancer.

These receptors allow T cells to sense and respond to diverse types of infection. CD8 + T cell exhaustion is defined by a unique transcriptional and epigenetic profile that is important to ...