Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

became better at activating the body’s own CD8 tumor-infiltrating lymphocytes—cells that directly attack cancer. This research doesn’t stand alone. A team at Memorial Sloan Kettering Cancer ...

CD8 + T cells that normally kill cancer cells ... due to the drug-enhanced activity of the CD8 + T-cells versus the drug alone. The first author, Kennady Bullock, developed a unique assay to ...

When the two antibodies were given together, they stimulated greater expansion of CD8+ T cells than either alone, implying they stimulate nonredundant pathways. In murine models of colon cancer ...

Non-lactating mice and mice immunized with CFA alone did not show any signs of autoimmunity ... γ-producing CD4+ T cells and of cytotoxic CD8+ T cells, which were not detectable in CFA-immunized ...

The tetramer stocks are typically used at a final dilution of 1:100 to 1:200, but your mileage may vary. With some tetramers (but not most), CD8 mediated binding has been observed. In other words, the ...