Analysis showed that 25–30% of these tumor-infiltrating neutrophils expressed the CD71 protein, which was notably absent from most of the other neutrophils outside the brain tumor. The team ...

This process activates the ARG1 gene in neutrophils, transforming them into agents that suppress the immune system’s anti-cancer efforts. Higher levels of the protein CD71, identified on 25-30% ...

conditionally activated ADC directed towards CD71 and has demonstrated encouraging anti-tumour activity in patients with squamous non-small cell lung cancer (NSCLC). Meanwhile, its clinical ...