The University of Birmingham researchers have identified CD70 as a key target to reduce the risk of graft-versus-host disease (GVHD) in blood cancer patients post-stem cell transplant. GVHD causes ...

Explore the detailed process of manufacturing CD70 motorcycle kicks, from selecting the right materials to the precision assembly. This journey of expert craftsmanship takes you inside the factory ...

The tumor necrosis factor (TNF) superfamily member CD70 (also known as TNFSF7) has previously been identified as a biomarker and potential target for the treatment of certain malignancies.

[53] MDX-1206, which also targets CD19, is conjugated to the same duocarmycin DNA alkylating agent found in the anti-CD70 ADC MDX-1203. MDX-1206 was shown to have significant activity in ...

“Because there’s a paucity of samples that are well characterized with EGFR inhibitor resistance, CD70 hasn’t been observed before,” says Heymach. CD70’s exact role is unclear, but it ...

The company is developing ALLO-501 to treat large B-cell lymphoma; ALLO-316, an allogeneic engineered CAR T-cell product targeting CD70; ALLO-819 to treat acute myeloid leukemia; ALLO-213 for the ...

A next-generation allogeneic CAR T-cell therapy, ALLO-329, works by targeting both CD19+ B-cells and CD70+ activated T-cells. Additionally, this candidate incorporates Allogene’s proprietary ...