The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...

Most HIV-negative adults have between 500 and 1500 CD4 cells in a cubic millimeter of blood. However, due to natural variation some people may have a CD4 count slightly outside the general range. It ...