T-cell activation involves two phases, enabling a more precise immune response. This insight may boost cancer immunotherapy effectiveness. A research team led by Wolfgang Kastenmüller and Georg ...

Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune ...

CD4-cell counts and T-cell activation levels were ... and higher LPS levels were associated with greater activation of CD8 + lymphocytes. CD8 + activation also was found to be higher in elite ...

When your body senses something is wrong—whether it's a damaged cell or a growing tumor—it can react in many ways. One of the most powerful is cellular senescence. This process stops a cell from ...

Century Therapeutics, Inc. (NASDAQ: IPSC) announced that its management team will host a live fireside chat on Tuesday, April 22, 2025, at 10:00 a.m. EDT to discuss ...

A team from the Max Planck Research Group for Systems Immunology at the University of Würzburg has identified a previously ...

Three days post viral infection CD8 T cells (red) re-arrest with antigen presenting cells (cyan), where they are supplied with IL-2 by CD4 T cells (yellow), which migrate in a stop and go pattern.

Cardiac sarcoidosis (CS) was a complication in about 10% of pulmonary sarcoidosis (PS) cases, investigators reported in Respiratory Medicine. The retrospective study assessed the prevalence, incidence ...

Immunophenotyping reveals CD4+/CD8+ coexpression and overexpression of TCL1A, which helps differentiate it from LGLLs. Despite recent therapeutic advances such as alemtuzumab and stem cell ...