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CD20 is a CD marker—a molecule on the cell surface that can be used to identify and type a particular cell in the body. CD20 is found on the surface of B cells (a type of immune system cell).
The four anti-CD20 drugs used in the U.S. to treat relapsing MS -- ocrelizumab, ofatumumab, and ublituximab (Briumvi; ...
Sauer and his team set out to investigate how mAbs bind to the B cell surface receptor CD20, a common immunotherapy target for some blood cancers. They started by treating human lymphoma cells with ...
Ocrevus is a humanized monoclonal antibody designed to target CD20-positive B cells, a specific type of immune cell thought to be a key contributor to myelin (nerve cell insulation and support ...
Rituximab, a lower-cost treatment, may be as effective at managing RRMS as the approved therapy Ocrevus, a new study from ...
Columvi's design involves a 2:1 structural format, targeting CD3 on T cells and CD20 on B cells. The company continues to explore Columvi as both a single agent and with other medicines for the ...