These data are in line with findings suggesting that variations in CD19 expression influence B cell selection and function 31. We have discussed two basic aspects of conditional gene targeting ...

he began preclinical studies that showed the potential clinical application of using autologous T cells that were genetically modified to target the CD19 antigen through the retroviral gene ...

When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker. A series of rodent experiments ...

The pipeline purge comes less than a year after Caribou cut 12% of staff and ended its natural killer cell therapy program in ...

The South San Francisco-based company continued its pivot from oncology to autoimmune disease last year by halting work on the allogeneic CD19-directed CAR NK, dubbed NKX019, in lymphoma to focus ...

SC291 is their CD19‑targeted allogeneic CAR-T candidate ... Sana Biotechnology is a biotech that focuses on gene modification platforms. SANA was initially founded back in 2018, and it’s ...

Chronic lymphocytic leukemia (CLL) cell–derived exosomes demonstrated the ability to alter healthy donor cell function and ...