Shanghai Pharmaceuticals Holding Co. Ltd. has identified C-C chemokine receptor type 4 (CCR4) antagonists reported to be useful for the treatment of asthma, allergic rhinitis, atopic dermatitis, ...

Its inhibition results in a muted or absent inflammatory response in patients with asthma and dermatitis. Although the exact functions of CCR4 are not known, recent studies indicate that CCR4 ...

The Phase IIa (NCT05935332) and Phase IIb trial (NCT05399368), which were evaluating the CCR4 antagonist in patients with asthma and atopic dermatitis respectively, have now been formally ...