a MAO-B = monoamine oxidase type B, MAO-A = monoamine oxidase type A. b Expressed as the molar concentration of drug required to inhibit enzyme activity by 50% (nmol/L). c Expressed as the ...

a MAO-B = monoamine oxidase type B, MAO-A = monoamine oxidase type A. b Expressed as the molar concentration of drug required to inhibit enzyme activity by 50% (nmol/L). c Expressed as the ...

Rasagiline demonstrates complete and selective inhibition of MAO-B and is at least five times ... tract and readily crosses the blood-brain barrier. The optimal therapeutic dosage is 0.5-1 mg ...