Every cell in our body has a sex. But most research so far has focused on our gonads—ovaries or testes—and not on the early ...

The way DNA folds inside the nucleus of brain cells may hold the key to understanding ... offer a new way to think about cancer beyond gene mutations, based on the way that genes are connected ...

HD is a genetic brain disorder caused by an expansion of C-A-G repeats in the huntingtin (HTT) gene. Everyone inherits two ...

PTC518 showed reduced HTT protein and plasma NfL levels in Huntington's patients, with signals of clinical benefit across ...

Pediatric pilocytic astrocytoma (PA) is a common type of low-grade brain tumor in children, influenced by specific genetic ...

The Huntington’s Disease Society of America (HDSA) is proud to mark 33 years of Huntington's Disease (HD) Awareness Month, a nationwide initiative dedicated to educating the public and empowering fami ...

Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new ...

Individuals who have an affected parent have a 50% chance of inheriting the gene mutation for HD and have the option to pursue genetic testing. [24] A person who has the HD mutation has a 100% ...

Their study reveals that Chol-HDOs bind tightly to serum proteins, allowing them to persist in the bloodstream and cross into brain tissue. These findings offer insights into gene-targeting ...

and brain cancers. While manipulating gene expression in brain cells holds tremendous promise for treating these conditions, effectively delivering gene-targeting drugs to the brain has remained an ...