In addition, they gave some of the mice navitoclax, a Bcl-2 inhibitor currently in clinical trials to treat cancer by accelerating programmed cell death. Compared to mice that only received RHZ, those ...

Cellular damage or certain types of cancer therapy trigger an apoptotic pathway mediated by the mitochondria — and regulated by the BCL-2 protein family. “Pro-survival BCL-2 proteins are ...

set the scene for what followed on the role of apoptosis in cancer biology. The discovery of the Bcl-2 protein family, as well as p53 and its involvement in regulating apoptosis, and the CD95 ...

A new research paper titled "Inhibitory effect of miR-377 on the proliferative and invasive behaviors of prostate cancer cells through the modulation of MYC mRNA via its interaction with BCL-2/Bax ...

Ascentage Pharma Group Corp. Ltd. said two of its novel candidates have been included in the 2025 Chinese Society of Clinical Oncology Guidelines, including its in-house developed Bcl-2 selective ...

In addition, they gave some of the mice navitoclax, a Bcl-2 inhibitor currently in clinical trials to treat cancer by accelerating programmed cell death. Compared to mice that only received RHZ ...