Barbiturates are a type of drug that slows down brain activity. Barbiturates have been used for several conditions, including insomnia, anxiety, muscle spasms, and seizures. However, this drug ...

Objectives: To evaluate high-dose barbiturates as a second-tier therapy for pediatric refractory intracranial hypertension complicating severe traumatic brain injury. Design: This is a ...

Diazepam 5mg; per 5mL; wintergreen-spice flavor. Diazepam is a benzodiazepine that exerts anxiolytic, sedative, muscle-relaxant, anticonvulsant and amnestic effects. Most of these effects are ...

Bradycardia with catecholamine-depleting drugs. Antagonized by NSAIDs, barbiturates, rifampin, phenytoin. May increase cardiac effects of calcium channel blockers, digitalis, lidocaine.

Ten (28%) patients had RICH controlled (ICP < 20 mm Hg) within 6 hours after starting high-dose barbiturates, while 26 patients did not (Table 1). Neither demographic nor injury features differed ...