The rationale for the use of anti-BAFF therapy in human SLE is evident from several preclinical studies... Belimumab, a humanized antibody against B-cell-activating factor (BAFF, also known as ...

In many patients, a surge in BAFF levels occur after rituximab treatment ... Healio: What have we learned from trials of rituximab in SLE that can be applied to current and future investigations ...

also known as TNFSF13B and BAFF), developed by Human Genome Sciences and GlaxoSmithKline, met the primary end point in a Phase III trial for systemic lupus erythematosus (SLE). If approved ...