Kelly-Anne Phillips, Joanne Kotsopoulos, Susan Domchek, Mary Beth Terry, James Chamberlain, Julie Bassett, Amber Aeilts, Irene Andrulis, Saundra Buys, Wanda Cui, Mary ...

But a significant association was only seen in BRCA1 carriers: BRCA1 carriers: HR 0.44 (95% CI 0.34-0.57) BRCA2 carriers: HR 0.85 (95% CI 0.64-1.15) As for the secondary endpoints of disease-free ...

Inherited mutations in the gene BRCA2 significantly increase the risk of carriers to breast and ovarian cancers. BRCA2, a crucial player in the body's DNA repair system, aids in repairing damaged DNA.

Mutations in BRCA2—a gene known to repair damaged DNA and suppress tumor formation—can predict an individual's predisposition to develop breast cancer, ovarian, prostate, pancreatic ...

Mutations in the human BRCA2 gene are associated with susceptibility to early-onset breast cancer, but it is unclear how the wild-type BRCA2 protein works. In the July 17 Proceedings of the National ...

Mutations in BRCA2 — a gene known to repair damaged DNA and suppress tumor formation — can predict an individual’s predisposition to develop breast cancer, ovarian, prostate, pancreatic, and other ...