Inherited mutations in the gene BRCA2 significantly increase the risk of carriers to breast and ovarian cancers. BRCA2, a crucial player in the body's DNA repair system, aids in repairing damaged DNA.

She thought nothing of the routine genetic testing ordered by her doctor until she got an email in March 2020 revealing she was BRCA2 positive. According to the National Cancer Institute ...

About one-third of patients had changes in a specific combination of four genes - BRCA2, CDH1, RHOA and TP53 - and those patients were more likely to die from their cancer or have it return ...

Pharmacogenomics. 2012;13(13):1523-1535. 5-year survival for stage III and IV (%): carriers, 38.1; noncarriers, 24.5 Median survival: p = 0.002 5-year survival for stage III and IV: p < 0.001 [46 ...