Do you have any thoughts about the effect of oral contraceptives on tubo-ovarian cancer risk in BRCA1/2 mutation carriers? Based on the observed age of onset of these tubo-ovarian cancers ...

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Patients with BRCA1/2-associated breast cancer have good survival outcomes and are living longer, but this raises the ...

It is recommended that prophylactic surgery should be performed as soon as possible, simply because of the early development of cancer in BRCA mutation carriers. Although ovarian cancer rarely ...

Recent investigation focuses on the effects of BRCA1 and BRCA2 tumor pathogenic variants (tPVs) within the parameters of two ...

Germline BRCA 1 and BRCA 2 test results were available for all 450 men. These revealed 27 germline BRCA2 variants (6%), but only two germline BRCA1 variants (0.5%), and one of these probably wasn ...

For instance, women with BRCA1/2 mutations may benefit from targeted therapies such as PARP inhibitors, which are designed to ...

In a setback for J&J’s Janssen-Cilag unit, however, the CHMP has said it recommends limiting use of Akeega to patients with BRCA1/2 mutations, which will put the drug at a disadvantage against ...

Liquid biopsies offer a simpler way to detect cancer. Unlike traditional biopsies, it uses a blood draw. It helps monitor ...