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Research shows how even one faulty copy of the BRCA1 gene can fuel breast cancer
People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...
DNA repair protein's unexpected structure may lead to new cancer treatments
A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...
The Scientist6d
Repairing BRCA1 science
after a five-member panel at the school alleged that he had tampered with data related to the antibody assay he developed to test how BRCA1 encodes a protein to repair DNA damage. His case is now ...
EurekAlert!1mon
BRCA1 gene mutations may not be key to prostate cancer initiation, as previously thought
Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...
Targeted Oncology13d
Expanding HRD and BRCA1/2 Testing Could Improve Access to Effective Treatments in Ovarian and Breast Cancer
A real-world study reveals the need for increased homologous repair deficiency and BRCA1/2 testing in patients with ovarian ...
MedPage Today20d
Isaac Allen on Risk of Second Primary Cancers After BRCA1/2 Breast Cancer
Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Patients with BRCA1/2-associated breast cancer have good survival outcomes and are living longer, but this raises the ...