It also shows that molecules known as BH3 mimetics can improve the effect of cancer treatments by preventing tumor adaptations to inhibitors of anaplastic lymphoma protein kinase (ALK), one of the ...

Discover how dynamic BH3 profiling can predict responses in lung cancer patients to ALK inhibitors, enhancing personalized ...

It also shows that molecules known as BH3 mimetics can improve the effect of cancer treatments by preventing tumor adaptations to inhibitors of anaplastic lymphoma protein kinase (ALK), one of the ...

The BH3 domain is an essential feature of all BCL2 members and comprises an amphipathic α-helical segment that mediates many protein interactions. However, when taken out of their biological ...