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It also shows that molecules known as BH3 mimetics can improve the effect ... in patients with non-small cell lung cancer who show molecular alterations in this oncogene. Currently, four ...
It also shows that molecules known as BH3 mimetics can improve the effect ... in patients with non-small cell lung cancer who show molecular alterations in this oncogene. Currently, four ...
including the development of BH3 domain mimetics. Now, the authors describe obatoclax, a novel small-molecule inhibitor of BCL2 family pro-survival proteins. Of particular interest is its activity ...
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Dynamic BH3 profiling offers personalized lung cancer therapiesIn this group, 5% of patients show molecular alterations in the ALK gene ... of Barcelona reveals that the functional assay dynamic BH3 profiling (DBP) can predict whether this treatment will ...
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