The Falke group is currently investigating the molecular mechanisms of on-off switching of components within the chemosensory array, especially the mechanisms by which transmembrane receptors bind ...

Researchers have discovered that mouse PD-1 is significantly weaker than human PD-1, calling into question their reliability ...

Transmembrane signaling systems include membrane-bound cell surface receptors and molecules called ... S1097-2765(03)00350-2. Jones, R. B. et al. A quantitative protein interaction network for ...

CD14 and the Fcγ receptors CD32 and CD64 belong to a group of cell surface receptors engaged in ... incorporated into the membrane of the Daudi B cell line. Cells were washed and subsequently ...

Rese-cel, previously called CABA-201, is a CAR T-cell therapy that's designed to treat MS by depleting B-cells.

Caribou Biosciences has launched a Phase 1 trial testing its CAR T-cell therapy CB-010 for lupus affecting the kidneys and ...

The Phase 1 GALLOP study evaluating the investigational CAR-T therapy, CB-010, for treatment of lupus nephritis has launched.

The cryo-EM images showed that the GAIN domain of the receptor assumed several different positions in relation to the cell surface. Each different position of the GAIN domain created a different ...

Plasmacytoid dendritic cells (pDC) primarily function as weak antigen-presenting cells (APC), but have also been shown to ...