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(The location of adhesion molecules in the B cell synapse was not explored ... express “natural antibodies”. These are immunoglobulin M (IgM) and, less commonly, IgG or IgA; they bind many ...
Researchers at the University of Colorado Anschutz Medical Campus have uncovered a critical, previously underappreciated role ...
Adoptive Cell Transfer (ACT) includes a class of immunotherapy approaches to treat cancer.  This procedure focuses on a ...
A new study finds that specific B-cell subsets at diagnosis may help predict remission in early rheumatoid arthritis, ...
Three doses of COVID-19 mRNA vaccination induce long-lasting antibody and memory B-cell responses, according to a study of 113 healthcare workers in Catalonia who were followed during three years.
Cross-linking Fcα/μR expressed on a pro-B cell line Ba/F3 transfectant with soluble IgM or IgM-coated microparticles induced internalization of the receptor. Fcα/μR also mediated primary B ...
which is a CD20 x CD3 bispecific IgM antibody designed to treat patients with B cell Non-Hodgkin's lymphoma and other B cell malignancies, IGM-8444, which is an IgM antibody targeting Death ...
A recently developed cancer treatment called chimeric antigen receptor T-cell therapy (CAR T-cell therapy, for short) offers hope to people whose diffuse large B-cell lymphoma (DLBCL) has proved ...
In yet another early year blow for the Bay Area’s biotech workforce, IGM Biosciences is laying off ... wrote that “the depth and consistency of B cell depletion is insufficient to meet our ...
Three doses of COVID-19 mRNA vaccination induce long-lasting antibody and memory B-cell responses, according to a study of 113 health care workers in Catalonia who were followed for three years.