Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

The self-reactive BCR repertoire enables B-1 cells to carry out their unique functions in regulating immunity. Additionally, NAbs can cross-react with pathogen epitopes, which ensures the early ...

The spleen is a very important large lymphoid organ consisting of the so-called red pulp which contains macrophages and other cellular elements and is richly bathed in blood entering from a network of ...

B cells are a subtype of lymphocyte. They form part of the adaptive immune response and mediate humoral immunity. B cells can produce high-affinity antibodies and generate immunological memory.

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

This is particularly promising for patients with B-cell malignancies, where unmet needs remain high." EXCELERIZE, the Phase 1, open-label, multicenter dose-escalation study will assess the safety ...