Adoptive Cell Transfer (ACT) includes a class of immunotherapy approaches to treat cancer.  This procedure focuses on a ...

Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 T cells, teaching them how to mount lasting defenses after vaccination. The study was recently published in ...

CAR T-cell product showed promising efficacy and safety in a phase I trial of lymphoma patients who had previously failed ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

Sarcopenia, a hallmark of cancer cachexia, is associated with poor outcomes in chimeric antigen receptor (CAR) T-cell therapy ...

A next-generation "armored" CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments, including ...

Lim and his team plan to further investigate this platform’s potential across different diseases, such as multiple sclerosis, and explore the interactions of these synthetic T cells with other ...

If you or a loved one has diffuse large B-cell lymphoma (DLBCL) that is no longer responding to treatment or came back after treatment, chimeric antigen receptor (CAR) T-cell therapy may be an option.