Our aptamers seek out these stem cells specifically and kill them ... After 72 hours, the aptamer alone had reduced the cancer cells in culture by 40%, demonstrating the aptamer's toxicity to ...

Our aptamers seek out these stem cells specifically and kill them effectively ... leukemia cell cultures as well as in live mice with leukemia. After 72 hours, the aptamer alone had reduced the cancer ...

More information: Francesco Millozzi et al, Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle ...

Our aptamers seek out these stem cells specifically and kill them ... After 72 hours, the aptamer alone had reduced the cancer cells in culture by 40 percent, demonstrating the aptamer's toxicity ...

When metabolite binds (+M), the switching sequence is incorporated into the aptamer domain, and the expression platform folds into a terminator stem-loop (T), causing transcription to abort.

For example, the FDA-approved aptamer drug Pegaptanib (Macugen) targets vascular endothelial growth factor (VEGF) for the treatment of age-related macular degeneration. Aptamers can be conjugated to ...

Our aptamers seek out these stem cells specifically and kill them ... After 72 hours, the aptamer alone had reduced the cancer cells in culture by 40 percent, demonstrating the aptamer's toxicity ...