More information: Francesco Millozzi et al, Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle ...

Aptamers, noted for their high specificity in therapeutics and diagnostics, are gaining traction due to advancements in SELEX technology and personal ...

Base-editing technologies along with AAV engineering not only help reduce costs but can also accelerate preclinical therapeutic development.

The ATLAS-seq technology combines a single-cell approach with an aptamer-based fluorescent molecular sensor that emits a fluorescence signal when a T cell is activated. In the study, the ...

The researchers tested the drug-delivering aptamers in leukemia cell cultures as well as in live mice with leukemia. After 72 hours, the aptamer alone had reduced the cancer cells in culture by 40 ...

Aptamers can be conjugated to drug molecules or nanoparticles to enable targeted drug delivery. The aptamer directs the drug to the desired tissue or cell type, reducing off-target effects and ...

TAGCyx is also advancing a number of programs to develop Xenoligo molecules that bind selectively to tumor cells. These can be used as a drug delivery tool by creating Xenoligo aptamer–drug ...

Optimer binders have been proven to work as vaccine adjuvants and will be further developed and commercialized for swine vaccines, with Aptamer to receive 10% on downstream sales of all Optimer ...

For the development of two bright multi-colour fluorogenic aptamer tags, and for demystifying the fluorescence activation mechanism, enabling efficient imaging of diverse RNAs in living cells.