After 72 hours, the aptamer alone had reduced the cancer cells in culture by 40 percent, demonstrating the aptamer's toxicity to the cancer, the researchers report. When the aptamers carried the ...

For example, the FDA-approved aptamer drug Pegaptanib (Macugen) targets vascular endothelial growth factor (VEGF) for the treatment of age-related macular degeneration. Aptamers can be conjugated to ...

Using an aptamer-based approach, SomaLogic can identify up to 7,000 proteins at high levels of specificity, providing real-time precision proteomics for use in the lab and the clinic. Genomics has ...