For example, the A allele of rs10423769, approximately 2 Mb upstream from the APOE gene (Rajabli et al., 2022), appears to protect against APOE4 by decreasing its expression (Vance et al., 2024; J.

The present study explored atherosclerosis in streptozotocin-induced diabetic apolipoprotein E-deficient (apoE-/-) mice that were randomized (n = 20) to receive for 20 weeks no treatment ...

The research focused on the effects of KLX on human umbilical vein endothelial cells (HUVECs) subjected to TGFβ1-induced EndMT and on atherosclerotic lesions in ApoE-/- mice fed a high-fat diet.