ESTHER study found that non-modifiable factors like age, sex, and APOE ε4 status significantly influence blood biomarker ...

In cognitively healthy middle-aged adults at risk for Alzheimer’s disease, becoming physically active, especially in line ...

ApoE protein is a lipid-binding protein expressed at the highest levels in the liver and brain, where it binds directly to Aβ present in plaques. Of the three common APOE gene alleles ...

Eisai and Biogen have received marketing authorisation from the European Commission (EC) for Leqembi (lecanemab) to treat ...

Biogen BIIB and partner Eisai announced that the European Commission (EC) has granted marketing authorization to Leqembi ...

In the European Union (EU), lecanemab is indicated for the treatment of adult patients with a clinical diagnosis of mild cognitive impairment and ...

1,2,4-7 Protofibrils are a key toxic form of Aβ that accumulate in the brain and ... or no copy (non-carriers) of the ApoE ε4 gene are less likely to experience ARIA than people with two ApoE ...

3 Lecanemab is the only approved Aβ monoclonal antibody that preferentially ... People with only one (heterozygous) or no copy (non-carriers) of the ApoE ε4 gene are less likely to experience ...