Apolipoprotein A4 (APOA4) is a protein produced by the small intestine in response to dietary fats. While it plays a vital role in controlling appetite and burning calories, its benefits are ...

Enzyme-linked immunosorbent assays were used to compare serum concentrations of TMAO, apolipoprotein A4 (APOA4), and proprotein convertase subtilisin/kexin type 9 (PCSK9) between patients with ...

TMAO upregulates hepatic PCSK9 gene expression while downregulating APOA4 expression. PCSK9 overexpression inhibits APOA4 expression, while low APOA4 expression further promotes PCSK9 expression ...