The cells interact with the matrix on the basal side, and things such as nutrients and drugs interact with the tissue inside the apical surface. Parasitic bacteria and viruses enter the intestine ...

Traditional methods produce organoids with a “basolateral-out” morphology, which prevents scientists from accessing the internally located apical surface. This surface is responsible for absorbing ...

Indeed, gamma-actin-deficient mice show altered architecture of the apical surface of epithelial cells and progressive hearing loss. A stiffer cortical membrane may be required to withstand the ...

4c), even though the chemokine was fully retained on the endothelial surface (data not shown ... applied to adherent lymphocytes at their apical endothelial contact with the EC-adsorbed chemokine.