Figure 2: Human APC and CTNNB1 mutations are associated with carcinogenesis. Figure 3: Cancer therapeutics that target components of the canonical Wnt pathway. Recent studies suggest that so ...

The APC gene was discovered by Kimmel Cancer Center ... Luo et al, HMGA1 acts as an epigenetic gatekeeper of ASCL2 and Wnt ...

Examination of the tumour suppressor adenomatous polyposis coli (APC) has shown that it may be multifunctional. Recent work has demonstrated dynamic interactions of APC with the microtubule ...