Enter the anti-CRISPR protein AcrVIB1, a promising inhibitor whose exact function has remained a mystery—until now. A research team from the Helmholtz Institute for RNA-based Infection Research ...

In bacteriophage genomes, researchers find three anti-CRISPR proteins that naturally inhibit CRISPR-Cas9 in one bacterial species and can do the same in human cells. Notably, the work is “going ...

Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other ...

The scientists found three proteins that block CRISPR, known as anti-CRISPRs. U of T Faculty of Medicine's Alan Davidson, a professor of molecular genetics and biochemistry, and Karen Maxwell, an ...

A prime example of this ongoing battle is the CRISPR-Cas defense system in bacteria, countered by anti-CRISPR proteins (Acrs) in phages, which specifically block these bacterial “gene scissors”.

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

The ongoing major projects in the laboratory focus on the structural biology of CRISPR-Cas surveillance complexes and their suppression by anti-CRISPR proteins (in collaboration with Luciano ...

We list below recent highlights on the CRISPR-Cas surveillance pathway. Anti-CRISPR protein targeting type VI CRISPR-Cas complex. Cas13 recognizes complementary viral transcripts to trigger ...

Enter the anti-CRISPR protein AcrVIB1, a promising inhibitor whose exact function has remained a mystery—until now. A research team from the Helmholtz Institute for RNA-based Infection Research (HIRI) ...