Systemic examination revealed some purpura over his lower limbs ... The bone marrow trephine and conjunctival biopsy were positive for amyloid deposition, showing apple-green birefringence ...

In people with amyloidosis, amyloid proteins can clump together and affect body tissues and organs, such as kidney and heart function. This can cause symptoms like fatigue and dizziness ...

Amyloidosis is a rare disease that involves the buildup of a specific protein called amyloid. Unlike other proteins, amyloid does not have a supportive role in the body. Instead, the buildup of ...

Twenty-seven of these patients were excluded because of treatment with steroids and/or a calcineurin inhibitor, vasculitis, amyloidosis, purpura nephritis, a transplanted kidney or absence of the ...

Since the early 1990s, many scientists have thought that removing clumps of a sticky protein called amyloid from the brains of Alzheimer’s patients could help slow the disease, if not stall or ...

Recent approvals by the Food and Drug Administration have focused on medications that shrink the sticky brain deposits of a protein called amyloid beta. The errant growth of this protein is ...

Researchers have now proposed a molecular mechanism that links amyloid deposition in the aortic valve with degenerative calcification. They also theorize that other risk factors for CAVD ...

An experimental drug that clears amyloid beta from the brain cut the risk of developing Alzheimer’s by 50% among a group of 22 people with genetic mutations that all but guarantee they would ...

There are three major subtypes of amyloidosis: primary amyloidosis, secondary amyloidosis, and hereditary amyloidosis (Khan & Falk, 2001; Nakata & Shimamoto, 2003; Smith, 2003). Primary ...

Amyloidosis is a group of rare disorders caused by deposition of misfolded proteins as insoluble fibrils, which leads to progressive multiorgan failure and death. 1 The past 30 years have seen ...

That’s because unconventional ideas that do not offer fealty to the dominant approach to study and treat Alzheimer’s — what’s known as the amyloid hypothesis — often find themselves ...

Alzheimer's disease starts with a sticky protein called amyloid beta that builds up into plaques in the brain, setting off a chain of events that results in brain atrophy and cognitive decline.