and initiated allopurinol 100 mg daily. A few days after the introduction of allopurinol, the patient developed severe urticaria/angioedema, and allopurinol therapy was discontinued. The patient ...

“Even using a high dose of allopurinol, if you would like to get lower than 3 mg/dL for intensive therapy, close to 50% of patients will fail,” he said. Pérez-Ruiz described a strategy of ...

Subjects received 100–300 mg/day of allopurinol plus standard therapy (n = 26), or standard therapy alone (n = 26). Standard therapy included antihypertensives and lipid-lowering drugs.