A Class I recall is issued by the U.S. Food and Drug Administration in situations that can have deadly consequences.

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

Despite major interest in this pathway for cancer drug discovery, no drugs have yet been approved that act specifically against PI3K or its downstream regulator, AKT. However, several drugs that ...

In amongst a clutch of discontinued phase 3 programmes in Roche's fourth-quarter results update was the news that it has stopped a study of AKT inhibitor ipatasertib as a treatment for first-line ...

Finnair cancels 70 flights due to union strikes, affecting around 6,500 passengers - Airline boss described the industrial action as ‘unreasonable’ ...

Warm weather is in view and it's time to get out on the water, so Alki Kayak Tours (1660 Harbor SW; WSB sponsor) is open for ...

AKT Trading Inc. is recalling lots of its prepared vegetables in California over botulism concerns. The U.S. Food and Drug Administration issued an alert, advising customers to discard any ...

The aberrant expression of partner of NOB1 homolog (PNO1) is known to promote oncogenesis in the colorectum and the esophagus, but its involvement in ovarian cancer and the mechanisms behind it are ...

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window The AKT inhibitor afuresertib failed to improve progression-free survival (PFS) when added to paclitaxel for patients ...

A new review was published in , Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer." ...