A study of real-world patients with ADPKD supports tolvaptan’s role in slowing annual eGFR decline. Treatment with tolvaptan modestly but significantly attenuates long-term decline of kidney ...

The role of polycystin 1 and 2 in the regulation of cell adhesion. The role of microRNAs in the pathogenesis of ADPKD. Trafficking of the polycystin proteins.

Autosomal dominant polycystic kidney disease (ADPKD) is the most common, potentially lethal genetic disorder characterized by the progressive enlargement of numerous fluid-filled cysts and the ...

Tamibarotene (RN-014) is a retinoic acid receptor agonist for which Rege Nephro is currently conducting a Phase 2 clinical trial in Japan in autosomal dominant polycystic kidney disease (ADPKD).

ADPKD, or autosomal dominant polycystic kidney disease, can cause severe pain, headaches, and more problems. What can you do to feel better and stay active? Find exercise and diet tips, pain ...